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Procedure

Personalized TMS for PTSD

N/A
Waitlist Available
Led By Bill Phillips, PhD
Research Sponsored by Wave Neuroscience
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 22 - 65 years
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up assessed at all treatment sessions and follow-up visit, a duration of up to 5 weeks
Awards & highlights

Study Summary

This trial studies a new treatment for PTSD in veterans and first responders. It involves 20 in-office treatments with EEG recordings to determine optimal treatment parameters.

Who is the study for?
This trial is for U.S. Military veterans or first responders aged 22-65 with PTSD who can consent to participate. It's not for pregnant women, those in other studies, people with uncontrolled health conditions, metal implants in the head, history of ECT/TMS, stroke, seizures or family history of seizures.Check my eligibility
What is being tested?
The study tests EEG-based personalized TMS treatment on participants with PTSD over a course of 20 sessions within 35 days. An initial EEG records brain activity to tailor the TMS therapy specifically for each individual.See study design
What are the potential side effects?
While not explicitly listed here, common side effects from TMS may include headache, scalp discomfort at the site of stimulation, tingling or spasms of facial muscles.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 22 and 65 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~assessed at all treatment sessions and follow-up visit, a duration of up to 5 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and assessed at all treatment sessions and follow-up visit, a duration of up to 5 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Treatment Safety

Trial Design

1Treatment groups
Experimental Treatment
Group I: Open-Label active EEG-based personalized TMS treatmentExperimental Treatment1 Intervention
20 sessions of EEG-based personalized TMS over a maximum of 21 days. Two sessions per treatment day. Each session consists of TMS treatment at 50% Motor Threshold, pulse frequency between 8-13 Hz. TMS delivery of 5 second pulse train, with an inter-train interval of 20 seconds. Session duration is 15 minutes. A rest period of at least 30 minutes is required between the 2 sessions in a treatment day.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
EEG-based personalized TMS
2023
N/A
~30

Find a Location

Who is running the clinical trial?

Wave NeuroscienceLead Sponsor
12 Previous Clinical Trials
886 Total Patients Enrolled
Bill Phillips, PhDPrincipal InvestigatorWave Neuroscience, Inc.
~20 spots leftby Jun 2025