Electrophysiology assessment - corticospinal tract for Spinal Cord Injury

N/A

Waitlist Available

Led By Ismael Seanez, PhD

Research Sponsored by Washington University School of Medicine

Eligibility Criteria Checklist

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Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 30 minutes before and 30 minutes into intervention

Awards & highlights

Study Summary

This trial will test if re-enabling movement of paralyzed areas is possible using transcutaneous spinal cord stimulation.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30 minutes before and 30 minutes into intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30 minutes before and 30 minutes into intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 minutes before and 30 minutes into intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in corticospinal tract excitability after training

Changes in reticulospinal tract excitability after training

Trial Design

2Treatment groups

Experimental Treatment

Group I: Reaction time evaluation during non-invasive spinal cord stimulation and leg movementsExperimental Treatment2 Interventions

This arm will receive the loud auditory stimuli to evaluate the excitability of the reticulospinal tract first then the arm will receive the transcranial magnetic stimulation to excite the corticospinal tract second

Group II: Evaluation of motor evoked potentials during non-invasive spinal cord stimulation and leg movementsExperimental Treatment2 Interventions

This arm will receive the transcranial magnetic stimulation to evaluate the excitability of the corticospinal tract first then the arm will receive the loud auditory stimuli to evaluate the excitability of the reticulospinal track second.

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Who is running the clinical trial?

Washington University School of MedicineLead Sponsor

1,945 Previous Clinical Trials

2,303,800 Total Patients Enrolled

Ismael Seanez, PhDPrincipal InvestigatorWashington University School of Medicine

1 Previous Clinical Trials

120 Total Patients Enrolled

~7 spots leftby May 2025

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