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Rehabilitation for Cervical Spondylosis

N/A
Recruiting
Research Sponsored by Western University, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured and reported for all follow-ups throughout study (i.e. pre-operatively, 4 weeks, 6 weeks, 6 months)
Awards & highlights

Study Summary

This trial aims to understand how rehabilitation therapy can improve brain plasticity and neurological function in patients with spinal cord compression. The study will compare patients who receive rehabilitation after spine surgery with those who do not,

Who is the study for?
This trial is for right-handed individuals with progressive neurological deficits lasting less than 24 months, who are eligible for MRI scans. It's designed to help those recovering from non-traumatic spinal cord injuries like spondylosis and cervical myelopathy.Check my eligibility
What is being tested?
The study tests how occupational therapy rehabilitation after spine surgery can improve brain plasticity and recovery of neurological function in patients with spinal cord injury, using advanced imaging techniques to track progress.See study design
What are the potential side effects?
Since the intervention involves occupational therapy rehabilitation, side effects may include muscle soreness or fatigue due to physical activity. However, these are typically mild and part of the recovery process.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured and reported for all follow-ups throughout study (i.e. pre-operatively, 4 weeks, 6 weeks, 6 months)
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured and reported for all follow-ups throughout study (i.e. pre-operatively, 4 weeks, 6 weeks, 6 months) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in Graded Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP) scores
Changes in levels of N-acetylaspartate (NAA) in the motor cortex
Changes to intensity of cortical activation in motor and supplementary motor cortices
+1 more
Secondary outcome measures
American Spinal Injury Association (ASIA) Impairment Scale
Modified Japanese Orthopaedic Association (mJOA) scale
Myelopathy Disability Index (MDI)
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: RehabilitationExperimental Treatment1 Intervention
Group II: No rehabilitationActive Control1 Intervention

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Who is running the clinical trial?

Western University, CanadaLead Sponsor
242 Previous Clinical Trials
57,467 Total Patients Enrolled
~8 spots leftby Dec 2025
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