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Behavioural Intervention

Computerized Cognitive Exercise Training for Multiple Sclerosis

N/A
Waitlist Available
Research Sponsored by Stony Brook University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Definite MS Diagnosis, any subtype
Ages 18-70
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12weeks
Awards & highlights

Study Summary

This trial is testing a new computer-based treatment for cognitive impairment in people with multiple sclerosis, to see if it is better than a control computer-based treatment.

Who is the study for?
Adults aged 18-70 with Multiple Sclerosis (MS) who have some cognitive impairment and can operate a computer may join this trial. They should be stable on their current medications, have no recent MS relapses or steroid treatments, and not suffer from other major neurological or psychiatric conditions that could affect cognition.Check my eligibility
What is being tested?
The study is testing a computerized cognitive exercise program called PACR designed to improve brain function in people with MS. Participants will use the program for 60 hours over 12 weeks, comparing its effectiveness against a control activity using similar time on a provided laptop.See study design
What are the potential side effects?
Since the intervention involves non-invasive computer exercises, there are no direct physical side effects expected from participating in this trial. However, participants might experience eye strain or fatigue from extended screen time.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with multiple sclerosis.
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I am between 18 and 70 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
A composite derived from a standardized battery of neuropsychological tests
Secondary outcome measures
A timed measure based on direct observation of functional performance

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Treatment AExperimental Treatment1 Intervention
plasticity-based, adaptive, computerized cognitive remediation (PACR)
Group II: Treatment BActive Control1 Intervention
Ordinary Computer Games (an "active control condition")

Find a Location

Who is running the clinical trial?

Stony Brook UniversityLead Sponsor
217 Previous Clinical Trials
39,850 Total Patients Enrolled
5 Trials studying Multiple Sclerosis
122 Patients Enrolled for Multiple Sclerosis
National Multiple Sclerosis SocietyOTHER
96 Previous Clinical Trials
9,386 Total Patients Enrolled
94 Trials studying Multiple Sclerosis
9,032 Patients Enrolled for Multiple Sclerosis
National Multiple Sclerosis Society (NMSS)UNKNOWN

Media Library

PACR (Plasticity-based, Adaptive, Computerized Cognitive Remediation) (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT02141386 — N/A
Multiple Sclerosis Research Study Groups: Treatment A, Treatment B
Multiple Sclerosis Clinical Trial 2023: PACR (Plasticity-based, Adaptive, Computerized Cognitive Remediation) Highlights & Side Effects. Trial Name: NCT02141386 — N/A
PACR (Plasticity-based, Adaptive, Computerized Cognitive Remediation) (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02141386 — N/A
~12 spots leftby Jun 2025
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