← Back to Search

Procedure

Digital nerve procedure for Pain (PAPDAP Trial)

N/A
Waitlist Available
Led By Scott N Loewenstein, MD
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up tinel's sign at 3 months; tinel's sign at 6 months
Awards & highlights

PAPDAP Trial Summary

This trial will compare three treatments for nerve pain after finger amputation: targeted muscle reinnervation (TMR), regenerative peripheral nerve interfaces (RPNI), and standard traction neurectomy (TN).

Eligible Conditions
  • Pain
  • Neuroma
  • Amputation

PAPDAP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~tinel's sign at 3 months; tinel's sign at 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and tinel's sign at 3 months; tinel's sign at 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
bMHQ
Secondary outcome measures
Grip strength
NPS
Other outcome measures
Tinel's sign

PAPDAP Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Targeted Muscle ReinnervationExperimental Treatment1 Intervention
Targeted Muscle Reinnervation - of digital sensory nerves at the time of amputation
Group II: Regenerative Peripheral Nerve InterfaceExperimental Treatment1 Intervention
Regenerative Peripheral Nerve Interface - of digital sensory nerves at the time of amputation
Group III: Traction NeurectomyActive Control1 Intervention
Traction neurectomy - of digital sensory nerves at the time of amputation.

Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor
993 Previous Clinical Trials
1,095,244 Total Patients Enrolled
6 Trials studying Pain
1,770 Patients Enrolled for Pain
American Society for Surgery of the HandOTHER
10 Previous Clinical Trials
1,042 Total Patients Enrolled
Scott N Loewenstein, MDPrincipal InvestigatorIndiana University
~7 spots leftby Jun 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top