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Photoacoustic Imaging for Head and Neck Cancers

N/A
Waitlist Available
Led By Anurag K Singh
Research Sponsored by Roswell Park Cancer Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 years
Awards & highlights

Study Summary

This trial is testing how well photoacoustic imaging works to measure tumors and normal tissue in patients with head and neck cancer.

Eligible Conditions
  • Head and Neck Cancer
  • Radiation Therapy Patient
  • Head and Neck Lymph Nodes
  • Head and Neck Squamous Cell Carcinoma
  • Laryngeal Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of PAI to quantify tumor characteristic in patients undergoing ALTENS (part II): rate
Feasibility of photoacoustic imaging (PAI) to quantify tumor characteristics (part I): rate
Secondary outcome measures
Body Weight Changes
Utility of serial PAI-based oxygen saturation (%sO2) measurements

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic (PAI, ALTENS)Experimental Treatment2 Interventions
PART I: Patients undergo PAI before the start of chemoradiation therapy, weekly during 7 weeks of chemoradiation, and again 3-4 months after completion of chemoradiation therapy. PART II (CANCER-FREE WITH XEROSTOMIA): Patients undergo PAI at baseline, up to twice during acupuncture-like transcutaneous nerve stimulation (ALTENS) therapy, once after ALTENS, and at 3-6 months follow up.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcutaneous Acupoint Electrical Stimulation
2014
N/A
~30

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,717 Previous Clinical Trials
40,953,350 Total Patients Enrolled
Roswell Park Cancer InstituteLead Sponsor
404 Previous Clinical Trials
31,287 Total Patients Enrolled
Anurag K SinghPrincipal InvestigatorRoswell Park Cancer Institute
5 Previous Clinical Trials
1,900 Total Patients Enrolled
~2 spots leftby Jun 2025
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