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Amino Acid Supplements for Muscle Building Post-Exercise (DiEx Trial)

N/A
Waitlist Available
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 minutes
Awards & highlights

DiEx Trial Summary

This trial investigates how different amino acid supplements affect muscle building & breakdown during resistance training. Results could benefit athletes & those with muscle wasting.

Who is the study for?
This trial is for trained individuals who've been doing structured exercises like weightlifting or team sports at least twice a week for the past three months. It's not suitable for those unable to follow the study rules, with certain medical conditions, on medications affecting protein metabolism, using illicit drugs or tobacco, amenorrheic women, or those taking supplements that could interfere with results.Check my eligibility
What is being tested?
The study compares the muscle-building effects of three supplements after resistance exercise: BCAA Supplement, Collagen Supplement and Di-Leucine Supplement. Using a 'breath test', blood and urine samples will help understand which supplement best promotes muscle growth and prevents breakdown.See study design
What are the potential side effects?
While specific side effects are not detailed in this summary, potential risks may include digestive discomfort from the supplements and typical post-exercise soreness or fatigue.

DiEx Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Whole-Body Protein Synthesis
Secondary outcome measures
Murine Cell-Based Experiments (ex-vivo experiments) - Protein Synthesis
Murine Cell-Based Experiments (ex-vivo experiments) - mTORC1 Signalling
Murine Cell-Based Experiments (ex-vivo experiments) -hypertrophy
+1 more

DiEx Trial Design

3Treatment groups
Experimental Treatment
Group I: Di-Leucine supplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing Di-Leucine following resistance exercise and their whole body anabolism will be determined over the subsequent 6 hours
Group II: Collagen SupplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing collagen protein following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Group III: BCAA SupplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing branched chain amino acids (BCAA) following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Collagen Supplement
2020
N/A
~110
BCAA Supplement
2017
N/A
~30

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
693 Previous Clinical Trials
1,020,074 Total Patients Enrolled

Media Library

Collagen Supplement Clinical Trial Eligibility Overview. Trial Name: NCT05754125 — N/A
Interventional. Research Study Groups: Collagen Supplement, Di-Leucine supplement, BCAA Supplement
Interventional. Clinical Trial 2023: Collagen Supplement Highlights & Side Effects. Trial Name: NCT05754125 — N/A
Collagen Supplement 2023 Treatment Timeline for Medical Study. Trial Name: NCT05754125 — N/A
~5 spots leftby Jun 2025
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