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High Added Sugar Meal for Healthy Eating

N/A
Waitlist Available
Research Sponsored by University of Delaware
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up over 2 weeks, at baseline and 3 hours post-consumption of each meal (low and high added sugar), separated by a 1-week washout
Awards & highlights

Study Summary

This trial will study the effects of added sugars on brain health in adults aged 30-64. Two meals will be provided, one with 16g of added sugars, and the other with 61g. Blood vessel function and brain structure will be examined using MRI.

Eligible Conditions
  • Healthy Eating
  • Healthy Aging

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~over 2 weeks, at baseline and 3 hours post-consumption of each meal (low and high added sugar), separated by a 1-week washout
This trial's timeline: 3 weeks for screening, Varies for treatment, and over 2 weeks, at baseline and 3 hours post-consumption of each meal (low and high added sugar), separated by a 1-week washout for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from baseline in cerebrovascular reactivity at 3 hours post-consumption of each meal
Change from baseline in hippocampal damping ratio at 3 hours post-consumption of each meal
Change from baseline in hippocampal stiffness after 3 hours post-consumption of each meal
+3 more
Secondary outcome measures
Change from baseline in blood pressure at 3 hours post-consumption of each meal
Change from baseline in hippocampal cerebrovascular reactivity at 3 hours post-consumption of each meal
Change from baseline in other lipid profile at 3 hours post-consumption of each meal
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Low Added Sugar MealExperimental Treatment1 Intervention
Participants will be provided a meal low in added sugars.
Group II: High Added Sugar MealExperimental Treatment1 Intervention
Participants will be provided a meal high in added sugars.

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Who is running the clinical trial?

University of DelawareLead Sponsor
154 Previous Clinical Trials
25,064 Total Patients Enrolled
Christopher Martens, PhDStudy DirectorUniversity of Delaware
~9 spots leftby May 2025
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