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Intracranial Monitoring Tasks for Language Disorders

N/A
Recruiting
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Between ages 18 - 85
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up throughout intracranial monitoring period, up to approximately 10 days
Awards & highlights

Study Summary

This trial will help researchers understand how the brain processes speech, which could lead to new treatments for speech disorders.

Who is the study for?
This trial is for adults aged 18-85 with language disorders or epilepsy who are already scheduled for intracranial monitoring of the left cerebral hemisphere. Participants must be able to follow test instructions and give informed consent.Check my eligibility
What is being tested?
The study investigates how the human brain processes language by having participants perform behavioral tasks during intracranial monitoring, aiming to combine neural data with computational models of cognition.See study design
What are the potential side effects?
Since this trial involves non-invasive behavioral tasks during a procedure that patients are already undergoing, there are no additional side effects directly associated with the study itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 85 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~throughout intracranial monitoring period, up to approximately 10 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout intracranial monitoring period, up to approximately 10 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Brain scores for diverse artificial neural network (ANN) language models
Cortical maps of linguistic responses
Neural time-courses during naturalistic language comprehension

Trial Design

1Treatment groups
Experimental Treatment
Group I: Epileptic participants undergoing intracranial monitoringExperimental Treatment1 Intervention
Patients with pharmaco-resistant epilepsy undergoing intracranial monitoring involving the left cerebral hemisphere.

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,947 Previous Clinical Trials
13,204,604 Total Patients Enrolled
Massachusetts Institute of TechnologyOTHER
97 Previous Clinical Trials
12,729,947 Total Patients Enrolled

Media Library

Epileptic participants undergoing intracranial monitoring Clinical Trial Eligibility Overview. Trial Name: NCT05222594 — N/A
Language Disorder Research Study Groups: Epileptic participants undergoing intracranial monitoring
Language Disorder Clinical Trial 2023: Epileptic participants undergoing intracranial monitoring Highlights & Side Effects. Trial Name: NCT05222594 — N/A
Epileptic participants undergoing intracranial monitoring 2023 Treatment Timeline for Medical Study. Trial Name: NCT05222594 — N/A
~14 spots leftby Mar 2026
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