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Speech Production Tasks for Understanding Speech Disorders

N/A
Waitlist Available
Led By Lingyun Zhao, PhD
Research Sponsored by University of California, San Francisco
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during inpatient hospitalization, up to 14 days after surgical electrode implantation
Awards & highlights

Study Summary

This trial seeks to understand how the brain controls the stopping of speech production, to help us understand communication disorders like stuttering & aphasia.

Who is the study for?
This trial is for individuals with medication-resistant epilepsy at UCSF who are undergoing surgical electrode implantation to locate their seizure focus. They must be willing and able to cooperate with study tasks involving speech production.Check my eligibility
What is being tested?
The study aims to understand how the brain stops ongoing speech, which is crucial for smooth conversations and turn-taking. It will explore neural mechanisms in patients performing speech tasks during electrode monitoring.See study design
What are the potential side effects?
Since this trial involves non-invasive speech production tasks, there are no direct side effects from interventions like drugs or surgery. However, participants may experience fatigue or stress from the tasks.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during inpatient hospitalization, up to 14 days after surgical electrode implantation
This trial's timeline: 3 weeks for screening, Varies for treatment, and during inpatient hospitalization, up to 14 days after surgical electrode implantation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean Change in Neural Activity
Secondary outcome measures
Number of sites with stimulation induced speech termination

Trial Design

1Treatment groups
Experimental Treatment
Group I: Voice and Electrocorticography (ECoG) recording during Speech Production TasksExperimental Treatment1 Intervention
Participants produce speech following visual cues on a computer while ECoG signals for neural activity and voice was recorded during their inpatient hospitalization at the University of California, San Francisco (UCSF).

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Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,517 Previous Clinical Trials
15,240,999 Total Patients Enrolled
15 Trials studying Epilepsy
6,086 Patients Enrolled for Epilepsy
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
331 Previous Clinical Trials
178,457 Total Patients Enrolled
3 Trials studying Epilepsy
109 Patients Enrolled for Epilepsy
Lingyun Zhao, PhDPrincipal InvestigatorUniversity of California, San Francisco

Media Library

Voice and Electrocorticography (ECoG) recording during Speech Production Tasks Clinical Trial Eligibility Overview. Trial Name: NCT05876910 — N/A
Epilepsy Research Study Groups: Voice and Electrocorticography (ECoG) recording during Speech Production Tasks
Epilepsy Clinical Trial 2023: Voice and Electrocorticography (ECoG) recording during Speech Production Tasks Highlights & Side Effects. Trial Name: NCT05876910 — N/A
Voice and Electrocorticography (ECoG) recording during Speech Production Tasks 2023 Treatment Timeline for Medical Study. Trial Name: NCT05876910 — N/A
~9 spots leftby Nov 2027
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