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Behavioural Intervention
CBT vs Mindfulness-Based Therapy for Autism
N/A
Recruiting
Led By Brenna Maddox, PhD
Research Sponsored by University of North Carolina, Chapel Hill
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
≥18 years of age
Co-occurring depression and/or anxiety as determined by a score ≥10 on the PHQ-ADS depression and/or anxiety subscale
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6-months follow-up
Awards & highlights
Study Summary
This trial will compare CBT & MBT, two treatments for depression & anxiety in autistic adults, to see which is more effective.
Who is the study for?
This trial is for English-speaking autistic adults over 18 living in North Carolina or Virginia. Participants must have a professional autism diagnosis or score high on an autism screening, and show signs of depression or anxiety. Those with acute mental issues, intoxication, mania, or at risk of suicide cannot join.Check my eligibility
What is being tested?
The study compares Cognitive-Behavioral Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT) to see which is more effective for treating depression and anxiety in autistic adults. Both therapies will be given through telehealth sessions.See study design
What are the potential side effects?
While CBT and MBCT are generally safe, some may experience increased anxiety, emotional discomfort during sessions, fatigue after therapy work, or frustration if expected improvements aren't seen.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 18 years old or older.
Select...
I have depression or anxiety with a score of 10 or more on the PHQ-ADS.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 6-months follow-up
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6-months follow-up
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in anxiety and depression symptoms
Secondary outcome measures
Change in disability
Change in functional impairment
Change in mental health
+7 moreTrial Design
2Treatment groups
Active Control
Group I: Cognitive-Behavioral Therapy (CBT)Active Control1 Intervention
The arm receives the Unified Protocol (UP), a modular transdiagnostic CBT treatment that uses a parsimonious approach to treatment by addressing common emotion-related mechanisms underlying both anxiety and depression.
Group II: Mindfulness-Based Cognitive Therapy (MBCT)Active Control1 Intervention
Mindfulness-Based Cognitive Therapy (MBCT) is an empirically supported treatment that focuses on non-judgmental acceptance of present moment experiences and emotions. MBCT was adapted from Mindfulness-Based Stress Reduction (MBSR) to focus on improving mental health more specifically in individuals with depression and other psychiatric conditions.
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Who is running the clinical trial?
University of North Carolina, Chapel HillLead Sponsor
1,522 Previous Clinical Trials
4,197,156 Total Patients Enrolled
Patient-Centered Outcomes Research InstituteOTHER
557 Previous Clinical Trials
29,949,078 Total Patients Enrolled
University of VirginiaOTHER
760 Previous Clinical Trials
1,250,126 Total Patients Enrolled
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