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Sound Stimulation for Auditory Processing

N/A
Waitlist Available
Led By Bharath Chandrasekaran, PhD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 13 years up to 25 years
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during eeg session, up to 3 hours
Awards & highlights

Study Summary

This trial will focus on understanding how the frequency-following response, a scalp-recorded neurophonic potential, is influenced by stimulus context, arousal state, and category relevance in neurotypical human participants.

Who is the study for?
This trial is for English or Mandarin speakers aged 13-25 with normal hearing and less than six years of music training. It's not for those with hearing loss, tinnitus, cognitive impairments, trouble understanding speech in noise, or proficiency in languages other than English/Chinese.Check my eligibility
What is being tested?
The study investigates how the brain responds to sounds and language using a neurophonic potential called FFR. It looks at how predictability, relevance of sound categories, and arousal state influence this response in healthy individuals.See study design
What are the potential side effects?
Since the interventions involve non-invasive sound stimulation without drugs or medical procedures, significant side effects are not expected. Participants may experience fatigue or discomfort from wearing headphones or scalp electrodes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 13 and 25 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during eeg session, up to 3 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and during eeg session, up to 3 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Arousal state and predictability effects on the FFRs
Pitch tracking and decoding accuracies for dynamically varying pitch in naturally produced Mandarin tone categories
Stimulus-specific effects in Chinese vs. English participants

Trial Design

1Treatment groups
Experimental Treatment
Group I: Neurotypical Human ParticipantsExperimental Treatment1 Intervention
Native speakers of Chinese and native speakers of English

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,731 Previous Clinical Trials
16,307,366 Total Patients Enrolled
Northwestern UniversityLead Sponsor
1,601 Previous Clinical Trials
915,594 Total Patients Enrolled
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
331 Previous Clinical Trials
178,417 Total Patients Enrolled
~28 spots leftby Jan 2026