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Riociguat for Sarcoidosis (RioSAPH Trial)

Phase 4
Waitlist Available
Led By Robert P Baughman, MD
Research Sponsored by University of Cincinnati
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48 weeks
Awards & highlights

RioSAPH Trial Summary

Double blind placebo controlled trial of riociguat for sarcoidosis associated pulmonary hypertension

Eligible Conditions
  • Sarcoidosis

RioSAPH Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Time until clinical worsening
Secondary outcome measures
Pulmonary function
Quality of life
Safety: adverse events
+1 more

RioSAPH Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: RiociguatActive Control1 Intervention
Active drug
Group II: PlaceboPlacebo Group1 Intervention
placebo

Find a Location

Who is running the clinical trial?

University of CincinnatiLead Sponsor
430 Previous Clinical Trials
634,431 Total Patients Enrolled
14 Trials studying Sarcoidosis
3,712 Patients Enrolled for Sarcoidosis
Robert P Baughman, MDPrincipal InvestigatorUniversity of Cincinnati
10 Previous Clinical Trials
2,530 Total Patients Enrolled
9 Trials studying Sarcoidosis
2,515 Patients Enrolled for Sarcoidosis
Steve Nathan, MDPrincipal InvestigatorInova Fairfax Hospital
~6 spots leftby Jun 2025