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Combination Chemotherapy for Pancreatic Cancer
Study Summary
This trial is testing a combination of drugs to see if they can shrink a pancreatic tumor before surgery and kill any remaining cells after surgery.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- Your blood tests for counts, hemoglobin, creatinine, bilirubin, AST, and ALT need to be within a certain range, and women of childbearing age must have a negative pregnancy test.My pancreatic cancer can be surgically removed and hasn't spread outside the pancreas.I do not have serious heart problems.I do not have a history of chronic diarrhea.I do not have any other type of cancer.I am fully active or can carry out light work.I do not have lung fibrosis or pneumonia.My organs are working well.I do not have uncontrolled seizures, active brain diseases, or known brain disorders.You have the tissue samples needed for the study.My diagnosis of pancreatic cancer is confirmed by lab tests.I do not have severe numbness or pain in my hands or feet.
- Group 1: Treatment (mFOLFIRINOX)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What evidence is there to suggest that leucovorin calcium does not pose a risk to human health?
"Due to the Phase 2 status of leucovorin calcium, our team at Power has rated its safety on a scale from 1-3 as a two. This means that while there is some data evidencing its security, no clinical evidence suggests efficacy."
At what facilities is this clinical experiment being conducted?
"Currently, the study is recruiting out of 9 different medical sites situated in Guilford, Fairfield and North Haven among other regions. It is best to select a clinic near you so as to reduce travel demands should you decide to join the trial."
Are there precedents of research into the effects of leucovorin calcium?
"Currently, 643 live clinical trials for leucovorin calcium are being conducted with 201 of these at Phase 3. Numerous medical centers in Guangzhou, Guangdong have started the trial process but there is a total of 27590 locations operating trials around the world."
What therapeutic purposes does leucovorin calcium typically treat?
"Leucovorin calcium is frequently employed to treat rectal carcinoma and other malignancies such as ovarian cancer, sarcoma, and colorectal carcinoma."
How many individuals have enrolled in this clinical research?
"Unfortunately, this trial is no longer inviting participants. Originally posted on March 25th 2014, the listing was last updated October 31st 2022; however, there are presently 1250 trials actively enrolling acinar cell adenocarcinoma of the pancreas patients and 643 studies for leucovorin calcium that are recruiting."
Does this research study still accept participants?
"This experiment is no longer enrolling patients. Initially posted on March 25th 2014, the most recent alteration occurred October 31st 2022. There are presently 1250 clinical trials actively seeking participants with acinar cell adenocarcinoma of the pancreas and 643 studies for leucovorin calcium currently recruiting volunteers."
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