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Hyperbaric Oxygen Therapy for Aging (HBOT Trial)

Phase 2 & 3
Waitlist Available
Research Sponsored by TruDiagnostic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up testing will compare baseline with 6 months
Awards & highlights

HBOT Trial Summary

This trial will test whether hyperbaric oxygen therapy can help improve epigenetic aging, inflammation, and cellular health.

HBOT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~testing will compare baseline with 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and testing will compare baseline with 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Epigenetic Aging
Secondary outcome measures
Neurotrax

Side effects data

From 2018 Phase 2 trial • 20 Patients • NCT02363959
10%
Repeat bronchoscopy due to bleeding during biopsy
100%
80%
60%
40%
20%
0%
Study treatment Arm
Hyperbaric Oxygen, Airway Biopsy
No Hyperbaric Oxygen, Airway Biopsy

HBOT Trial Design

3Treatment groups
Experimental Treatment
Group I: Arm 3: Crossover ArmExperimental Treatment1 Intervention
Patients will have 3 months of no treatment, and then be randomized to receive either high pressure or mild pressure HBOT
Group II: Arm 2: High pressure HBOTExperimental Treatment1 Intervention
"High" pressure HBOT: 100% O2 @ 14 PSI for 100 minutes 3x/week for 6 weeks, 2 weeks off, and then an additional 4 weeks of therapy. Followed by 3 months of no treatment
Group III: Arm 1: Mild pressure HBOTExperimental Treatment1 Intervention
"Mild" pressure HBOT: 100% O2 @ 4.2 PSI for 100 minutes 3x/week for 6 weeks, 2 weeks off, and then an additional 4 weeks of therapy. Followed by 3 months of no treatment
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hyperbaric Oxygen Therapy
2016
Completed Phase 4
~800

Find a Location

Who is running the clinical trial?

TruDiagnosticLead Sponsor
11 Previous Clinical Trials
456 Total Patients Enrolled
8 Trials studying Aging
346 Patients Enrolled for Aging
~9 spots leftby May 2025
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