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Nonsteroidal Anti-inflammatory Drug

Salsalate Oral Tablet for Prophylaxis of Preeclampsia

Phase < 1
Waitlist Available
Led By Anna Stanhewicz, PhD
Research Sponsored by University of Iowa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment
Awards & highlights

Study Summary

This trial is investigating why women who develop preeclampsia during pregnancy are more likely to develop cardiovascular disease later in life, in order to identify better clinical management of cardiovascular disease risk in these women.

Eligible Conditions
  • Prophylaxis of Preeclampsia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
change in endothelial function following salsalate treatment compared to placebo treatment
Secondary outcome measures
change in inflammatory response to ang II compared to baseline

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: SalsalateExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Location

Who is running the clinical trial?

Penn State UniversityOTHER
357 Previous Clinical Trials
125,955 Total Patients Enrolled
University of IowaLead Sponsor
454 Previous Clinical Trials
882,006 Total Patients Enrolled
Anna Stanhewicz, PhDPrincipal Investigator - University of Iowa
University of Iowa
3 Previous Clinical Trials
74 Total Patients Enrolled
~5 spots leftby Jun 2025
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