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Adavosertib Before Surgery for Ovarian Cancer
Study Summary
This trial is studying how a drug affects the DNA of patients with advanced ovarian cancer to see if it can help doctors plan more effective treatment.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2023 Phase 1 & 2 trial • 76 Patients • NCT02095132Trial Design
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Who is running the clinical trial?
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- You have other cancers that are currently being treated, unless certain exceptions apply.You have major symptoms from the suspected illness.You have not received treatment before for a specific type of ovarian, fallopian tube, or peritoneal cancer.Your blood and other body chemical levels need to be within certain normal ranges.You are able to perform daily activities without any limitations or with only slight restrictions.Be careful if you are taking certain medications or herbal supplements that might interact with the study drug.You need to have a negative pregnancy test within 3 days before starting the study.You cannot take certain medications because they might interfere with the study drug.You have advanced-stage high grade serous ovarian, fallopian tube, or primary peritoneal carcinoma based on certain clinical signs.You have received treatment for ovarian, fallopian tube, or primary peritoneal cancer before.You have a brain disease that is not stable or being treated.You need to meet certain heart and heart rhythm requirements.
- Group 1: Treatment (adavosertib)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many individuals are being recruited for participation in this trial?
"Correct. Per the details provided on clinicaltrials.gov, this research is actively searching for volunteers; beginning February 4th 2016 and last edited April 19th 2022. The experiment requires 30 participants to be recruited across 10 trial sites."
Are there any vacancies left for participants in this experiment?
"This research is actively enrolling volunteers. Clinicaltrials.gov records indicate that this trial was initially advertised on February 4th 2016 and recently revised on April 19th 2022."
Are there any American locales where this scientific investigation is being conducted?
"The 10 sites that are running this trial include MD Anderson in The Woodlands, MD Anderson West Houston in Houston, and The Woman's Hospital of Texas in Sugar Land; there are other centres involved as well."
Are there existing records of Adavosertib being tested in other experiments?
"The initial analysis of adavosertib was conducted in 2013 at University of Alabama's Birmingham Cancer Center. To date, 591 medical trials concerning this drug have concluded while 17 are still ongoing, with a considerable number originating from The Woodlands, Texas."
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